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Nitisinone 2MG/5MG/10MG: Diagnosis and treatment of tyrosinemia type I

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Lasinone, available in 2mg, 5mg, and 10mg capsules, is prescribed to individuals of all ages with confirmed Hereditary Tyrosinemia Type-1 (HT-1) in combination with a diet restricting phenylalanine and tyrosine. This medication helps manage HT-1, a genetic disorder that affects amino acid metabolism, preventing the accumulation of harmful substances in the body. Lasinone plays a crucial role in controlling the condition when used alongside dietary restrictions, making it a valuable treatment option for both adults and pediatric patients with HT-1.

Hereditary Tyrosinemia Type-1 (HT-1) is a rare genetic disorder causing tyrosine metabolism issues, often requiring lifelong treatment. This condition results from a deficiency of the enzyme fumarylacetoacetate hydrolase (FAH), leading to the abnormal accumulation of tyrosine and its metabolites in the body, particularly in the liver. If left untreated, HT-1 can lead to severe liver disease and other complications. Early diagnosis and management are vital, typically involving a special low-protein diet, medication, and, in severe cases, liver transplantation. Lifelong monitoring and adherence to the treatment plan are essential for individuals with HT-1 to lead healthy lives, making it critical to raise awareness of this rare genetic disorder.